TM4SF1

Sequence similarities

Belongs to the L6 tetraspanin family.

Tissue specificity

Highly expressed in lung, breast, colon and ovarian carcinomas. It is also present on some normal cells, endothelial cells in particular.

Cellular localization

• Membrane
• Multi-pass membrane protein
• Colocalizes with SDCBP2 in the apical region of the cell (PubMed:11102519).

Alternative names

• Transmembrane 4 L6 family member 1
• Membrane component chromosome 3 surface marker 1
• Tumor-associated antigen L6
• M3S1
• TAAL6
• TM4SF1

Database links

• entrezGene:4071
• omim:191155
• swissprot:P30408

Target type

Proteins

Primary research area

Immuno-oncology

Molecular weight

21632Da