TM9SF2
Function
In the intracellular compartments, may function as a channel or small molecule transporter.
Sequence Similarities
Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
Tissue Specificity
Ubiquitously expressed. Especially abundant in pancreas, highly expressed in kidney, lower levels in heart, brain, skeletal muscle and placenta. Lowest expression in lung and liver.
Cellular localization
- Endosome membrane
- Multi-pass membrane protein
- Golgi outpost
- Cytoplasm
- Cytoskeleton
- Microtubule organizing center
- Localizes to the postsynaptic Golgi apparatus region, also named Golgi outpost, which shapes dendrite morphology by functioning as sites of acentrosomal microtubule nucleation.
Alternative names
Transmembrane 9 superfamily member 2, p76, TM9SF2