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TMBIM4

Function

Anti-apoptotic protein which can inhibit apoptosis induced by intrinsic and extrinsic apoptotic stimuli. Can modulate both capacitative Ca2+ entry and inositol 1,4,5-trisphosphate (IP3)-mediated Ca2+ release.

Sequence Similarities

Belongs to the BI1 family. LFG subfamily.

Cellular localization

Alternative names

GAAP, LFG4, CGI-119, TMBIM4, Protein lifeguard 4, Golgi anti-apoptotic protein, Protein S1R, Transmembrane BAX inhibitor motif-containing protein 4, Z-protein

swissprot:Q9HC24 entrezGene:51643