TMED7
Function
Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Appears to play a role in the biosynthesis of secreted cargo including processing and post-translational modifications.
Post-translational modifications
N-linked glycosylated in complex form containing terminal sialic acid.
Sequence Similarities
Belongs to the EMP24/GP25L family.
Cellular localization
- Endoplasmic reticulum membrane
- Single-pass type I membrane protein
- Golgi apparatus
- cis-Golgi network membrane
- Single-pass type I membrane protein
- Endoplasmic reticulum-Golgi intermediate compartment membrane
- Single-pass type I membrane protein
- Cytoplasmic vesicle
- COPI-coated vesicle membrane
- Single-pass type I membrane protein
- Cytoplasmic vesicle
- COPII-coated vesicle membrane
- Single-pass type I membrane protein
- Cycles between compartments of the early secretatory pathway.
Alternative names
CGI-109, TMED7, Transmembrane emp24 domain-containing protein 7, p24 family protein gamma-3, p27, p24gamma3