TMEM259
Function
May have a role in the ERAD pathway required for clearance of misfolded proteins in the endoplasmic reticulum (ER). Promotes survival of motor neurons, probably by protecting against ER stress.
Sequence Similarities
Belongs to the membralin family.
Cellular localization
- Endoplasmic reticulum membrane
- Multi-pass membrane protein
Alternative names
C19orf6, TMEM259, Membralin, Transmembrane protein 259