TMEM59L
Function
Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of APP. Inhibits APP transport to the cell surface and further shedding.
Sequence Similarities
Belongs to the TMEM59 family.
Tissue Specificity
Expressed preferentially at high level in the brain.
Cellular localization
- Golgi apparatus membrane
- Single-pass type I membrane protein
Alternative names
BSMAP, C19orf4, TMEM59L, Transmembrane protein 59-like, Brain-specific membrane-anchored protein