TMPRSS5
Function
May play a role in hearing.
Involvement in disease
Defects in TMPRSS5 may be a cause of deafness.
Sequence Similarities
Belongs to the peptidase S1 family.
Tissue Specificity
Brain-specific. Predominantly expressed in neurons, in their axons, and at the synapses of motoneurons in the spinal cord.
Cellular localization
- Cell membrane
- Single-pass type II membrane protein
Alternative names
Transmembrane protease serine 5, Spinesin, TMPRSS5