Tnfrsf12a

Receptor for TNFSF12/TWEAK (By similarity). Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.

Highly expressed in fetal heart, intestine, kidney, liver, lung and skin, and in adult heart and ovary. Intermediate expression in adult kidney, lung and skin.

• Membrane
• Single-pass type I membrane protein

CD266, Fgfrp2, Fn14, Tnfrsf12a, Tumor necrosis factor receptor superfamily member 12A, Fibroblast growth factor-inducible immediate-early response protein 14, Fibroblast growth factor-regulated protein 2, Tweak-receptor, FGF-inducible 14, TweakR

• entrezGene:27279
• swissprot:Q9CR75

Proteins

Immuno-oncology

• Immunology & Infectious Disease

13641Da