Tnfrsf13b
Function
Receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. Involved in the stimulation of B- and T-cell function and the regulation of humoral immunity (By similarity).
Cellular localization
- Membrane
- Single-pass type III membrane protein
Alternative names
CD267, Taci, Tnfrsf13b, Tumor necrosis factor receptor superfamily member 13B, Transmembrane activator and CAML interactor