Tnfrsf17
Function
Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK (By similarity).
Tissue Specificity
Detected in spleen, thymus, bone marrow and heart, and at lower levels in kidney and lung.
Cellular localization
- Membrane
- Single-pass type III membrane protein
Alternative names
CD269, Bcm, Bcma, Tnfrsf17, Tumor necrosis factor receptor superfamily member 17, B-cell maturation protein