Skip to main content

Function

Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway (By similarity).

Tissue specificity

Preferentially expressed in activated T lymphocytes.

Cellular localization

  • Isoform A
  • Cell membrane
  • Single-pass type I membrane protein
  • Isoform B
  • Cell membrane
  • Single-pass type I membrane protein
  • Isoform C
  • Cell membrane
  • Single-pass type I membrane protein
  • Isoform D
  • Secreted

Alternative names

Gitr, Tnfrsf18, Tumor necrosis factor receptor superfamily member 18, Glucocorticoid-induced TNFR-related protein

Target type

Proteins

Primary research area

Immuno-oncology

Molecular weight

25334Da

We found 7 products in 3 categories

Primary Antibodies

Target

Reactive species

Proteins & Peptides

Target

Species of origin

Nature