TNFRSF8

Receptor for TNFSF8/CD30L (PubMed:8391931). May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B (PubMed:8999898).

Phosphorylated on serine and tyrosine residues (Probable). Isoform 2 is constitutively phosphorylated (PubMed:8839832).

Belongs to the TNFR8 family.

Isoform 2

Detected in alveolar macrophages (at protein level).

• Isoform 1
• Cell membrane
• Single-pass type I membrane protein
• Isoform 2
• Cytoplasm

CD30, D1S166E, TNFRSF8, Tumor necrosis factor receptor superfamily member 8, CD30L receptor, Ki-1 antigen, Lymphocyte activation antigen CD30

• entrezGene:943
• omim:153243
• swissprot:P28908

Proteins

Immuno-oncology

• Immunology & Infectious Disease

63747Da