Tnfrsf8

Function

Receptor for TNFSF8/CD30L (PubMed:8543792). May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B (By similarity).

Sequence Similarities

Belongs to the TNFR8 family.

Tissue Specificity

Detected in thymus and in activated splenocytes.

Cellular localization

• Cell membrane
• Single-pass type I membrane protein

Alternative names

CD30, Tumor necrosis factor receptor superfamily member 8, CD30L receptor, Lymphocyte activation antigen CD30, Tnfrsf8

Database links

swissprot:Q60846 entrezGene:21941

Other research areas

• Immunology & Infectious Disease