TNFSF15

Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis.

Belongs to the tumor necrosis factor family.

Specifically expressed in endothelial cells. Detected in monocytes, placenta, lung, liver, kidney, skeletal muscle, pancreas, spleen, prostate, small intestine and colon.

• Membrane
• Single-pass type II membrane protein
• Tumor necrosis factor ligand superfamily member 15, secreted form
• Secreted

TL1, VEGI, TNFSF15, Tumor necrosis factor ligand superfamily member 15, TNF ligand-related molecule 1, Vascular endothelial cell growth inhibitor

• entrezGene:9966
• omim:604052
• swissprot:O95150

Proteins

Immunology & Infectious Disease

28087Da