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TNFSF9

Function

Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages.

Sequence Similarities

Belongs to the tumor necrosis factor family.

Tissue Specificity

Expressed in brain, placenta, lung, skeletal muscle and kidney.

Cellular localization

Alternative names

Tumor necrosis factor ligand superfamily member 9, 4-1BB ligand, 4-1BBL, TNFSF9

swissprot:P41273 omim:606182 entrezGene:8744