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Tnfsf9
Function
Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages.
Sequence similarities
Belongs to the tumor necrosis factor family.
Tissue specificity
Expressed in brain, placenta, lung, skeletal muscle and kidney.
Cellular localization
- Membrane
- Single-pass type II membrane protein
Alternative names
- Tumor necrosis factor ligand superfamily member 9
- 4-1BB ligand
- 4-1BBL
- TNFSF9
Database links
Target type
Proteins
Primary research area
Immuno-oncology
Molecular weight
26625Da