TNP1

Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction.

Belongs to the nuclear transition protein 1 family.

Expressed by spermatids (at protein level).

• Nucleus
• Chromosome
• Loaded onto the nucleosomes of condensing spermatids.

Spermatid nuclear transition protein 1, STP-1, TP-1, TNP1

• entrezGene:7141
• omim:190231
• swissprot:P09430

Proteins

Developmental Biology

6424Da