TPGS1
Function
Subunit of the tubulin polyglutamylase complex (TPGC). The complex mediates cilia and flagella polyglutamylation which is essential for their biogenesis and motility (Probable). May act in the targeting of the tubulin polyglutamylase complex. Required for the development of the spermatid flagellum (By similarity).
Cellular localization
- Cytoplasm
- Cytoskeleton
- Cilium axoneme
- Cytoplasm
- Cytoskeleton
- Flagellum axoneme
- Cytoplasm
- Cytoskeleton
- Cilium basal body
- Cytoplasm
- Cytoskeleton
- Flagellum basal body
- Cell projection
- Axon
- Cell projection
- Dendrite
- Cytoplasm
- Cytoskeleton
- Microtubule organizing center
- Centrosome
- Cytoplasm
- Cytoskeleton
- Microtubule organizing center
- Centrosome
- Centriolar satellite
- Associated with microtubules from neurites, centrosomes, basal bodies and axonemes.
Alternative names
C19orf20, TPGS1, Tubulin polyglutamylase complex subunit 1, PGs1