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Tpsab1

Developmental stage

Is not expressed in mature serosal or mucosal mast cells and is expressed only transiently at an early stage of in vitro mast cell differentiation.

Function

Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity (By similarity).

Sequence Similarities

Belongs to the peptidase S1 family. Tryptase subfamily.

Alternative names

Mcpt7, Tpsab1, Tryptase, Mast cell protease 7, Tryptase alpha/beta-1, mMCP-7

swissprot:Q02844 entrezGene:100503895