TPST1

Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.

N-glycosylated.

Belongs to the protein sulfotransferase family.

Ubiquitous. Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

• Golgi apparatus membrane
• Single-pass type II membrane protein

Protein-tyrosine sulfotransferase 1, Tyrosylprotein sulfotransferase 1, TPST-1, TPST1

• entrezGene:8460
• omim:603125
• swissprot:O60507

Proteins

42188Da