TPST2
Function
Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.
Post-translational modifications
N-glycosylated.
Sequence Similarities
Belongs to the protein sulfotransferase family.
Tissue Specificity
Widely expressed.
Cellular localization
- Golgi apparatus membrane
- Single-pass type II membrane protein
Alternative names
Protein-tyrosine sulfotransferase 2, Tyrosylprotein sulfotransferase 2, TPST-2, TPST2