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Tpt1

Developmental stage

Preferentially synthesized in cells of the early growth phase of Ehrlich ascites tumor.

Function

Involved in calcium binding and microtubule stabilization (By similarity). Acts as a negative regulator of TSC22D1-mediated apoptosis, via interaction with and destabilization of TSC22D1 protein (By similarity).

Sequence Similarities

Belongs to the TCTP family.

Cellular localization

Alternative names

Trt, Tpt1, Translationally-controlled tumor protein, TCTP, 21 kDa polypeptide, p21, p23

swissprot:P63028 entrezGene:22070