The MATH/TRAF domain binds to receptor cytoplasmic domains.
Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Mediates activation of NF-kappa-B and probably JNK. Seems to be involved in apoptosis. Plays a role in mediating activation of NF-kappa-B by EIF2AK2/PKR.
Ubiquitinated at Lys-318 by the SCF(FBXL2) complex, leading to its degradation by the proteasome.
Belongs to the TNF receptor-associated factor family. A subfamily.
Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon, and peripheral blood.
RNF84, TRAF5, TNF receptor-associated factor 5, RING finger protein 84
Proteins
Immunology & Infectious Disease
64406Da
We found 5 products in 2 categories
ab137763