TRAK2
Function
May regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR.
Post-translational modifications
O-glycosylated.
Sequence Similarities
Belongs to the milton family.
Tissue Specificity
Widely expressed, with highest expression in heart.
Cellular localization
- Cytoplasm
- Early endosome
- Mitochondrion
- Colocalizes with MGARP at the mitochondria. Translocates from the cytoplasm to the mitochondria in a MGARP-dependent manner (By similarity).
Alternative names
ALS2CR3, KIAA0549, TRAK2, Trafficking kinesin-binding protein 2, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein