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Transcription factor Sp4

Domain

The 9aaTAD motif is a transactivation domain present in a large number of yeast and animal transcription factors. In SP4, the motif is inactive.

Function

Binds to GT and GC boxes promoters elements. Probable transcriptional activator.

Sequence Similarities

Belongs to the Sp1 C2H2-type zinc-finger protein family.

Tissue Specificity

Abundant in brain.

Cellular localization

Alternative names

Transcription factor Sp4, SPR-1, SP4

swissprot:Q02446 entrezGene:6671 omim:600540