Plays an essential role in total transketolase activity and cell proliferation in cancer cells; after transfection with anti-TKTL1 siRNA, total transketolase activity dramatically decreases and proliferation was significantly inhibited in cancer cells. Plays a pivotal role in carcinogenesis.
Belongs to the transketolase family.
Overexpressed in hepatoma cancer cells.
Transketolase-like protein 2, TKTL2
Proteins
Metabolism
67877Da
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