Transketolase-like protein 2
Function
Plays an essential role in total transketolase activity and cell proliferation in cancer cells; after transfection with anti-TKTL1 siRNA, total transketolase activity dramatically decreases and proliferation was significantly inhibited in cancer cells. Plays a pivotal role in carcinogenesis.
Sequence Similarities
Belongs to the transketolase family.
Tissue Specificity
Overexpressed in hepatoma cancer cells.
Alternative names
Transketolase-like protein 2, TKTL2