Transmembrane 6 superfamily member 2
Function
Regulator of liver fat metabolism influencing triglyceride secretion and hepatic lipid droplet content (PubMed:24531328, PubMed:24927523). May function as sterol isomerase (PubMed:25566323).
Sequence Similarities
Belongs to the TM6SF family.
Tissue Specificity
Substantial expression in liver and intestine, whereas all other tissues analyzed show low levels.
Cellular localization
- Endoplasmic reticulum membrane
- Multi-pass membrane protein
- Endoplasmic reticulum-Golgi intermediate compartment membrane
- Multi-pass membrane protein
Alternative names
Transmembrane 6 superfamily member 2, TM6SF2