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Function

Plays a role in vesicular transport from endoplasmic reticulum to Golgi.

Involvement in disease

Encephalopathy, progressive, early-onset, with episodic rhabdomyolysis

PEERB

An autosomal recessive disease characterized by progressive encephalopathy exacerbated by febrile illness and associated with severe neurodevelopmental delay, episodes of rhabdomyolysis, developmental regression, epilepsy and tetraplegia.

None

The disease may be caused by variants affecting the gene represented in this entry.

Sequence similarities

Belongs to the TRAPP small subunits family. Sedlin subfamily.

Tissue specificity

Expressed in testis, liver, bladder, lung, spleen and brain, several cell lines and primary chondrocytes cell line.

Cellular localization

  • Cytoplasm
  • Perinuclear region
  • Endoplasmic reticulum
  • Golgi apparatus

Alternative names

HSPC126, TRAPPC2L, Trafficking protein particle complex subunit 2-like protein

Target type

Proteins

Molecular weight

16059Da

We found 1 product in 1 category

Proteins & Peptides

Target

Species of origin

Search our catalogue for 'TRAPPC2L' (1)

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