TREH
Function
Intestinal trehalase is probably involved in the hydrolysis of ingested trehalose.
Involvement in disease
Trehalase deficiency
TREHD
An autosomal recessive condition characterized by the inability to digest trehalose, a disaccharide found in mushrooms, products containing baker's yeast, and dried food. Individuals with trehalase deficiency suffer from abdominal pain, increased rectal flatulence, and diarrhea due to osmotic water flow into the colon.
None
The gene represented in this entry is involved in disease pathogenesis.
Sequence Similarities
Belongs to the glycosyl hydrolase 37 family.
Tissue Specificity
Expressed in kidney, liver and small intestine. Also more weakly expressed in pancreas.
Cellular localization
- Cell membrane
- Lipid-anchor
- GPI-anchor
Alternative names
TREA, TREH, Trehalase