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TREX2

Function

Exonuclease with a preference for double-stranded DNA with mismatched 3' termini. May play a role in DNA repair.

Sequence Similarities

Belongs to the exonuclease superfamily. TREX family.

Tissue Specificity

Detected in heart, breast, prostate, skeletal muscle, testis, uterus, bone marrow, colon, small intestine, stomach and thymus.

Cellular localization

Alternative names

Three prime repair exonuclease 2, 3'-5' exonuclease TREX2, TREX2

swissprot:Q9BQ50 entrezGene:11219 omim:300370