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TRIB2

Domain

The protein kinase domain is predicted to be catalytically inactive.

Function

Interacts with MAPK kinases and regulates activation of MAP kinases. Does not display kinase activity (By similarity).

Sequence Similarities

Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. Tribbles subfamily.

Tissue Specificity

Highly expressed in peripheral blood leukocytes.

Cellular localization

Alternative names

TRB2, TRIB2, Tribbles homolog 2, TRB-2

swissprot:Q92519 omim:609462 entrezGene:28951