TRIM47
Function
E3 ubiquitin-protein ligase that mediates the ubiquitination and proteasomal degradation of CYLD.
Pathway
Protein modification; protein ubiquitination.
Sequence Similarities
Belongs to the TRIM/RBCC family.
Tissue Specificity
Low expression in most tissues. Higher expression in kidney tubular cells. Overexpressed in astrocytoma tumor cells.
Cellular localization
- Cytoplasm
- Nucleus
Alternative names
GOA, RNF100, TRIM47, E3 ubiquitin-protein ligase TRIM47, Gene overexpressed in astrocytoma protein, RING finger protein 100, Tripartite motif-containing protein 47