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TRPT1

Function

Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate.

Sequence Similarities

Belongs to the KptA/TPT1 family.

Tissue Specificity

Widely expressed. Weakly or not expressed in lung, spleen, small intestine and peripheral blood leukocytes.

Alternative names

tRNA 2'-phosphotransferase 1, TRPT1

swissprot:Q86TN4 entrezGene:83707 omim:610470