TTC7B
Function
Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane. The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis. In the complex, plays a central role in bridging PI4KA to EFR3B and HYCC1, via direct interactions (PubMed:26571211).
Cellular localization
- Cytoplasm
- Cytosol
- Cell membrane
- Localizes to the cytosol and is recruited to the plasma membrane following interaction with EFR3 (EFR3A or EFR3B) (PubMed:23229899).
Alternative names
TTC7L1, TTC7B, Tetratricopeptide repeat protein 7B, TPR repeat protein 7B, Tetratricopeptide repeat protein 7-like-1, TPR repeat protein 7-like-1