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Function

Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.

Post-translational modifications

Sulfonation of the reactive cysteine Cys-30 enhances the stability of the native conformation of TTR, avoiding misassembly of the protein leading to amyloid formation.

Sequence similarities

Belongs to the transthyretin family.

Tissue specificity

Detected in plasma (at protein level). Detected in liver.

Cellular localization

  • Secreted

Alternative names

Transthyretin, Prealbumin, Ttr

Target type

Proteins

Primary research area

Neuroscience

Molecular weight

15776Da

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