TXLNG
Function
May be involved in intracellular vesicle traffic. Inhibits ATF4-mediated transcription, possibly by dimerizing with ATF4 to form inactive dimers that cannot bind DNA. May be involved in regulating bone mass density through an ATF4-dependent pathway. May be involved in cell cycle progression.
Sequence Similarities
Belongs to the taxilin family.
Tissue Specificity
Ubiquitously expressed. Expressed at high level in heart and skeletal muscle. Expressed in brain, placenta, lung, liver, kidney and pancreas.
Cellular localization
- Nucleus membrane
- Cytoplasm
- Cytosol
Alternative names
CXorf15, ELRG, LSR5, TXLNG, Gamma-taxilin, Environmental lipopolysaccharide-responding gene protein, Factor inhibiting ATF4-mediated transcription, Lipopolysaccharide-specific response protein 5, FIAT