UBE2E2

Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. Catalyzes the ISGylation of influenza A virus NS1 protein.

Protein modification; protein ubiquitination.

Autoubiquitinated in vitro.

Belongs to the ubiquitin-conjugating enzyme family.

UBCH8, UBE2E2, Ubiquitin-conjugating enzyme E2 E2, E2 ubiquitin-conjugating enzyme E2, UbcH8, Ubiquitin carrier protein E2, Ubiquitin-protein ligase E2

• entrezGene:7325
• omim:602163
• swissprot:Q96LR5

Proteins

22255Da