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UBE2Z

Function

Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity). Specific substrate for UBA6, not charged with ubiquitin by UBE1. May be involved in apoptosis regulation.

Pathway

Protein modification; protein ubiquitination.

Sequence Similarities

Belongs to the ubiquitin-conjugating enzyme family.

Tissue Specificity

Widely expressed. Highly in placenta, pancreas, spleen and testis.

Cellular localization

Alternative names

HOYS7, UBE2Z, Ubiquitin-conjugating enzyme E2 Z, E2 ubiquitin-conjugating enzyme Z, Uba6-specific E2 conjugating enzyme 1, Ubiquitin carrier protein Z, Ubiquitin-protein ligase Z, Use1

swissprot:Q9H832 entrezGene:65264 omim:611362