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Uchl4

Function

Ubiquitin-protein hydrolase is involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin.

Sequence Similarities

Belongs to the peptidase C12 family.

Tissue Specificity

Expressed in various tissues at low level.

Cellular localization

Alternative names

Ubiquitin carboxyl-terminal hydrolase isozyme L4, UCH-L4, Ubiquitin thioesterase L4, Uchl4

swissprot:P58321 entrezGene:93841