UCKL1

May contribute to UTP accumulation needed for blast transformation and proliferation.

Pyrimidine metabolism; CTP biosynthesis via salvage pathway; CTP from cytidine: step 1/3.

Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uridine: step 1/1.

Ubiquitinated by RNF19B; which induces proteasomal degradation.

Belongs to the uridine kinase family.

Ubiquitous.

• Cytoplasm
• Nucleus
• EBNA3 induces isoform 1 translocation to the nucleus, whereas it does change isoform 3 location.

URKL1, F538, UCKL1, Uridine-cytidine kinase-like 1

• entrezGene:54963
• omim:610866
• swissprot:Q9NWZ5

Proteins

61141Da