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Function

May be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of fetal cartilage and at the cartilage-bone interface.

Post-translational modifications

Proteolytically cleaved by a furin-like convertase to generate a persistent C-terminal fragment found in almost the entire cartilage matrix, and affecting osteoblast differentiation.

Sulfated on tyrosine residues.

Sequence similarities

Belongs to the UCMA family.

Tissue specificity

Predominantly expressed in resting chondrocytes.

Cellular localization

  • Secreted
  • Extracellular space
  • Extracellular matrix

Alternative names

C10orf49, UCMA, Unique cartilage matrix-associated protein

Target type

Proteins

Primary research area

Oncology

Molecular weight

16563Da

We found 1 product in 1 category

Proteins & Peptides

Target

Species of origin

Search our catalogue for 'UCMA' (1)

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