UCMA
Function
May be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of fetal cartilage and at the cartilage-bone interface.
Post-translational modifications
Proteolytically cleaved by a furin-like convertase to generate a persistent C-terminal fragment found in almost the entire cartilage matrix, and affecting osteoblast differentiation.
Sulfated on tyrosine residues.
Sequence Similarities
Belongs to the UCMA family.
Tissue Specificity
Predominantly expressed in resting chondrocytes.
Cellular localization
- Secreted
- Extracellular space
- Extracellular matrix
Alternative names
C10orf49, UCMA, Unique cartilage matrix-associated protein