udp
Function
Catalyzes the reversible phosphorylytic cleavage of uridine to uracil and ribose-1-phosphate (PubMed:16751). Shows weak activity towards deoxyuridine and thymidine (PubMed:16751). The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis (Probable).
Pathway
Pyrimidine metabolism; UMP biosynthesis via salvage pathway; uracil from uridine (phosphorylase route): step 1/1.
Sequence Similarities
Belongs to the PNP/UDP phosphorylase family.
Cellular localization
- Cytoplasm
Alternative names
b3831, JW3808, udp, Uridine phosphorylase, UPase, UrdPase