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UFSP1

Function

Thiol-dependent isopeptidase that specifically mediate the processing of UFM1 precursors as well as the deconjugation of UFM1 from target proteins (PubMed:35525273, PubMed:35926457). Mainly responsible for the maturation of the UFM1 precursor, a prerequisite for conjugation reactions (PubMed:35525273, PubMed:35926457).

Sequence Similarities

Belongs to the peptidase C78 family.

Cellular localization

Alternative names

Ufm1-specific protease 1, UfSP1, UFSP1

entrezGene:402682 swissprot:Q6NVU6 omim:611481