UL42

Plays an essential role in viral DNA replication by acting as the polymerase accessory subunit. Associates with the viral polymerase to increase its processivity and forms high-affinity direct interactions with DNA. Facilitates the origin-binding protein UL9 loading onto DNA thus increasing its ability to assemble into a functional complex capable of unwinding duplex DNA.

Belongs to the herpesviridae DNA polymerase processivity factor family.

• Host nucleus

DNA polymerase processivity factor, DNA-binding protein UL42, Polymerase accessory protein, PAP, UL42

• swissprot:P10226

Proteins

51159Da