UNCX
Function
Transcription factor involved in somitogenesis and neurogenesis. Required for the maintenance and differentiation of particular elements of the axial skeleton. May act upstream of PAX9. Plays a role in controlling the development of connections of hypothalamic neurons to pituitary elements, allowing central neurons to reach the peripheral blood circulation and to deliver hormones for control of peripheral functions (By similarity).
Sequence Similarities
Belongs to the paired homeobox family. Unc-4 subfamily.
Cellular localization
- Nucleus
Alternative names
UNCX4.1, UNCX, Homeobox protein unc-4 homolog, Homeobox protein Uncx4.1