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URAD

Function

Catalyzes the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin.

Pathway

Purine metabolism; urate degradation; (S)-allantoin from urate: step 3/3.

Sequence Similarities

Belongs to the OHCU decarboxylase family.

Tissue Specificity

Apparently not expressed.

Cellular localization

Alternative names

PRHOXNB, URAD, Putative 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase, OHCU decarboxylase, Parahox neighbor, Ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase

swissprot:A6NGE7 entrezGene:646625