USF1
Function
Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') that is found in a variety of viral and cellular promoters.
Involvement in disease
Hyperlipidemia, familial combined, 1
FCHL1
A disorder characterized by a variable pattern of elevated levels of serum total cholesterol, triglycerides or both. It is observed in a percentage of individuals with premature coronary heart disease.
None
Disease susceptibility is associated with variants affecting the gene represented in this entry.
Cellular localization
- Nucleus
Alternative names
BHLHB11, USF, USF1, Upstream stimulatory factor 1, Class B basic helix-loop-helix protein 11, Major late transcription factor 1, bHLHb11