USP29
Function
Deubiquitinase involved in innate antiviral immunity by mediating 'Lys-48'-linked deubiquitination of CGAS, thereby promoting its stabilization.
Sequence Similarities
Belongs to the peptidase C19 family.
Cellular localization
- Cytoplasm
- Perinuclear region
- Localizes to perinuclear region in response to herpes simplex virus-1 (HSV-1) infection.
Alternative names
Ubiquitin carboxyl-terminal hydrolase 29, Deubiquitinating enzyme 29, Ubiquitin thioesterase 29, Ubiquitin-specific-processing protease 29, USP29