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USP43

Function

May recognize and hydrolyze the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins (By similarity).

Sequence Similarities

Belongs to the peptidase C19 family.

Tissue Specificity

Expressed in brain, aorta and lung at low levels.

Alternative names

Ubiquitin carboxyl-terminal hydrolase 43, Deubiquitinating enzyme 43, Ubiquitin thioesterase 43, Ubiquitin-specific-processing protease 43, USP43

swissprot:Q70EL4 entrezGene:124739