VAMP5

May participate in trafficking events that are associated with myogenesis, such as myoblast fusion and/or GLUT4 trafficking.

(Microbial infection) Targeted and hydrolyzed by C.botulinum neurotoxin type X (BoNT/X) which hydrolyzes the 40-Arg-|-Ser-41 bond and probably inhibits neurotransmitter release (PubMed:28770820). It remains unknown whether BoNT/X is ever produced, or what organisms it targets.

Belongs to the synaptobrevin family.

• Cell membrane
• Single-pass type IV membrane protein
• Endomembrane system
• Single-pass type IV membrane protein
• Golgi apparatus
• trans-Golgi network membrane
• Single-pass type IV membrane protein
• Associated with the plasma membrane as well as intracellular perinuclear and peripheral vesicular structures of myotubes. Associated with the trans-Golgi, but not with the cis-Golgi apparatus (By similarity).

HSPC191, VAMP5, Vesicle-associated membrane protein 5, VAMP-5, Myobrevin

• entrezGene:10791
• omim:607029
• swissprot:O95183

Proteins

Neuroscience

12805Da