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Vasopressin-neurophysin 2-copeptin

Function

Neurophysin 2

Specifically binds vasopressin.

Arg-vasopressin

Has a direct antidiuretic action on the kidney, it also causes vasoconstriction of the peripheral vessels. Acts by binding to vasopressin receptors (V1bR/AVPR1B, V1aR/AVPR1A, and V2R/AVPR2) (PubMed:18174156).

Involvement in disease

Diabetes insipidus, neurohypophyseal

NDI

A disease characterized by persistent thirst, polydipsia and polyuria. Affected individuals are apparently normal at birth, but characteristically develop symptoms of vasopressin deficiency during childhood.

None

The disease is caused by variants affecting the gene represented in this entry.

Sequence similarities

Belongs to the vasopressin/oxytocin family.

Cellular localization

  • Secreted

Alternative names

ARVP, VP, AVP, Vasopressin-neurophysin 2-copeptin, AVP-NPII

Target type

Proteins

Primary research area

Neuroscience

Molecular weight

17325Da

We found 6 products in 2 categories

Primary Antibodies

Target

Reactive species

Proteins & Peptides

Target

Species of origin

Nature